Statistical model-based testing to evaluate the recurrence of genomic aberrations
نویسندگان
چکیده
منابع مشابه
Statistical model-based testing to evaluate the recurrence of genomic aberrations
MOTIVATION In cancer genomes, chromosomal regions harboring cancer genes are often subjected to genomic aberrations like copy number alteration and loss of heterozygosity. Given this, finding recurrent genomic aberrations is considered an apt approach for screening cancer genes. Although several permutation-based tests have been proposed for this purpose, none of them are designed to find recur...
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ژورنال
عنوان ژورنال: Bioinformatics
سال: 2012
ISSN: 1367-4803,1460-2059
DOI: 10.1093/bioinformatics/bts203